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奥美拉唑
奥美拉唑
别称: 洛塞克;欧麦亚砜;亚砜米唑;左旋奥美拉唑;艾美拉唑
英文名称: Omeprazole
CAS号: 73590-58-6
分子式: C17H19N3O3S
分子量: 345.42
熔点: 156°C
沸点: 600.0±60.0 °C(Predicted)
密度: 1.332 g/cm3
储存条件: 2-8°C
溶解度在水中的溶解度: 0.5 mg/mL
形态: 固体
稳定性: 稳定,但有吸湿性和光敏性。与强氧化剂不相容。避光保存。
 
结构式:
 
化学性质: 从乙腈结晶,熔点156℃。
 
用途: 奥美拉唑是一种质子泵抑制剂,对动物和人胃酸分泌具有很强的和较长时间的抑制作用。
 

A by UV

Ratio of absorbance is 1.6 to 1.8

1.7

B by IR

IR Conforms to the standard

Positive

C by TLC

Conforms to the standard

Positive

Appearance of solution

Solution should be clear

Solution is clear

Absorbance

At 440nm is not more than 0.1

0.02

Impurity C

BY TLC, not more intense than 0.1%

0.1%

Related substances by HPLC

 

 

Any individual impurity

Not more than 0.1%

0.1%

Residual solvent

 

 

Acetone

Not more than 5000ppm

Below detection limit

Methanol

Not more than 3000ppm

Below detection limit

Dichloromethane

Not more than 100ppm

Below detection limit

Acetonitrile

Not more than 410ppm

Below detection limit